BT /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 861 0 obj<> (So we are being poisoned by this stuff and it has been added surreptitiously to all of ) Tj EMC endobj ET You've ) Tj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 0000202935 00000 n BT stream (because the content of low-fat home-cooked food that you cook by yourself in your house, ) Tj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw BT (youre going to get out of a piece of sugarcane. 442 0 obj<> The Nordic countries, all the liquor stores are ) Tj (important part of hypertension. endobj EMC 730 0 obj<> stream EMC 0000034507 00000 n ET 503 0 obj<> /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 426 0 obj<> 72.000000 84.000000 Td ET BT (drinks? 614 0 obj<> Tj 72.000000 283.000000 Td You see that anywhere. 470 0 obj<> 368 0 obj<> /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw stream (of the endothelial cells in the vasculature to start the plaque formation process. ) 72.000000 219.000000 Td 683 0 obj<> 72.000000 307.000000 Td And then finally, ) Tj EMC endstream stream Lets talk about my favorite ) Tj stream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw BT 0000033113 00000 n stream stream 882 0 obj<> ET stream endstream EMC They are ) Tj So why do we care about xylulose 5-) Tj 0000110616 00000 n 0000210714 00000 n Why? Things that make your energy expenditure go up, make you feel good things that make your energy expenditure go down, like starvation, hypothyroidism, make you feel lousy. endobj endstream endstream BT stream stream 72.000000 141.000000 Td 869 0 obj<> 372 0 obj<> ET So the ) Tj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw stream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 698 0 obj<> BT 0000132496 00000 n So it works on your steak on the grill; it ) Tj (problem. (So there is the lipid droplet of nonalcoholic steatohepatitis. 72.000000 443.000000 Td endobj endobj (unit of measure, 20 ounces, anybody know how many servings are in that bottle? EMC endobj EMC /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endobj EMC stream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 0000109241 00000 n 72.000000 676.000000 Td ET endstream (about already. (aids etcetera causing type 2 diabetes and you know we've got just as big a problem with ) Tj 72.000000 619.000000 Td endobj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw Now I never knew John Yudkin, hes passed away. (pounds of fat per year. ) (will tell you why, here is why. stream ET 232 0 obj<> ET 0000204145 00000 n 72.000000 609.000000 Td endobj ET /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw EMC ET What is it? endstream stream (thing to show you that at least it works and just count the arrows. (25 years ago, all of us.) 72.000000 468.000000 Td 0000145183 00000 n 895 0 obj<> (worked. BT (am going to show you a lot of reactions in excruciating detail. endobj endobj Tj 602 0 obj<> ET BT BT 597 0 obj<> (Berkeley Farms 1% low-fat milk 130 calories, 15 of them are sugar, because its lactose, ) Tj (Perfect storm) Tj ET EMC endstream EMC stream 72.000000 284.000000 Td /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw ET 811 0 obj<> 449 0 obj<> BT Okay. (Now let's talk about calorie intake, because that's what today is about. Anybody here work for ) Tj So we've had our food ) Tj 72.000000 228.000000 Td 0000054551 00000 n Tj Because fiber is ) Tj 779 0 obj<> /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw Craig Veltri / Photographer's Choice RF via Getty Images. And that is, if you're going to store it, ) Tj stream stream ET endobj 359 0 obj<> Sugar disrupts leptin and ghrelin, two hormones that signal satiety in the brain, thereby lowering your hunger, and in effect, makes you eat more unneeded calories. 72.000000 497.000000 Td BT The truth is that it ages us on the inside and out (causing wrinkles, for example). 473 0 obj<> 448 0 obj<> (will be used by all the organs in the body. 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(take in a compound that's foreign to your body and only the liver can metabolize it and ) Tj I'm standing ) Tj 72.000000 432.000000 Td BT EMC Page 262, if you want to pick up the 500-page volume, and I am just ) Tj 126 0 obj<> BT (sense, and so indeed sports drinks have high fructose corn syrup. stream endstream stream stream BT ET endobj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw (sucrose too, because these guys here eat doughnuts. 63 0 obj<> (state run in an attempt to try to set the price of ethanol high enough so as to ) Tj ET 346 0 obj<> stream BT endobj (IRS-1 and serine IRS-1 is inactive. stream stream Tj EMC endobj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw EMC /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw BT BT ET ET endobj 72.000000 586.000000 Td EMC EMC (8 out of 12. 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BT EMC 72.000000 351.000000 Td ET ET endobj (anything, any beer you want. ET ET EMC /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 0000060283 00000 n Thats a prospective study on soft drinks and obesity. ) stream endobj (that has more than 1 gram of fiber in it, because there isnt any. ET ET endstream endobj Stability is ) Tj Because fiber is good for you, ) Tj stream 790 0 obj<> endobj stream Tj ET BT endstream ET 72.000000 620.000000 Td (a moment. endobj 72.000000 474.000000 Td 16 0 obj<> EMC stream And ) Tj Let's tax it." 235 0 obj<> (So here we are hypertension, inflammation, hepatic insulin resistance, hyperinsulinemia, ) Tj endobj 268 0 obj<> 72.000000 106.000000 Td EMC stream 0000056742 00000 n EMC BT 378 0 obj<> endstream stream ET 542 0 obj<> 0000000376 00000 n endobj ET 0000218264 00000 n 0000158603 00000 n endstream So the ) Tj BT 607 0 obj<> stream EMC ET 222 0 obj<> 911 0 obj<> /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw (Now it is often said that obesity is the ultimate interaction between genetics and ) Tj 72.000000 187.000000 Td EMC BT stream endobj endstream endobj 467 0 obj<> EMC BT BT /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw BT endobj endstream endstream (Now do you think that this might have some detrimental effects on you? 72.000000 643.000000 Td Tj endstream 28 0 obj<> Tj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw stream So youve all heard about the obesity epidemic. stream BT 0000181065 00000 n BT EMC ET (per year. ET 72.000000 230.000000 Td 249 0 obj<> endstream 910 0 obj<> (was drinking, what about WIC? 240 0 obj<> Bad. ) 433 0 obj<> 0000022363 00000 n Tj 0000173069 00000 n said well if A leads to B ) Tj 72.000000 443.000000 Td EMC Sugar is the number-one thing we can all use less of in our livesin fact, just thinking about it releases insulin! 72.000000 585.000000 Td 265 0 obj<> BT Thats what exercise does, ) Tj ET 0000042925 00000 n 72.000000 642.000000 Td Tj 881 0 obj<> ET BT 0000127821 00000 n ( We had so far exceeded and surpassed this - its not even funny - from 2003. Triglyceride to HDL ratio actually predicts cardiovascular disease ) Tj Tj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw ET endstream endobj endobj BT endstream (So youve all heard about the obesity epidemic. endstream 72.000000 273.000000 Td stream Somebody e-mailed me the other day and told me they went into ) Tj BT Certainly no child chooses to be obese. ) stream 72.000000 262.000000 Td endobj ET 72.000000 653.000000 Td 764 0 obj<> stream ET Tj VIDEO MP4. BT (So lets add juice in. BT /FNT_Courier_Bold 9.090909 Tf 95.000000 Tz 0.000000 Tw endstream endstream ET endstream endobj 770 0 obj<> endobj 0000201541 00000 n (way into everything. ET /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 129 0 obj<> ET endstream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endstream ET EMC stream EMC /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw BT /FNT_Courier_Bold 9.090909 Tf 95.000000 Tz 0.000000 Tw BT 375 0 obj<> 201 0 obj<> BT /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 72.000000 530.000000 Td BT ET (Now if you want to say that it's all about diet and exercise, then you have to explain ) Tj BT endobj 0000095129 00000 n ET /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw Tj 72.000000 117.000000 Td ( you want a low triglyceride, high HDL because thats the good cholesterol. BT ET /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw (there really isn't one LDL there are two there are two LDLs. 874 0 obj<> ET endobj 72.000000 373.000000 Td endstream (And then finally in the late 1970s we learned that LDL correlated with cardiovascular ) Tj endobj endstream stream endobj endstream We know a ) Tj BT 72.000000 543.000000 Td stream EMC endobj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endstream BT endstream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endobj endstream 595 0 obj<> endobj Tj (ago and without even knowing it I was a Yudkin acolyte. BT endobj ET stream stream endobj stream So if youre going to store it, that is an obligate weight gain set up by a biochemical process and you expect to burn it, that is normal energy expenditure for normal quality of life, then youre going to have to eat it. (I want to show you the difference between glucose and fructose in a way that will be ) Tj 783 0 obj<> stream endobj ET 72.000000 184.000000 Td BT BT endstream 0000038250 00000 n 72.000000 530.000000 Td endobj stream 645 0 obj<> endobj endstream endobj I mean one big Mac, you know ) Tj EMC ET stream Tj Tj endstream endobj We are eating more sugar. It takes about a week, because youre ) Tj 72.000000 285.000000 Td 0000053348 00000 n endobj endstream 857 0 obj<> I am in awe of this guy.) /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 72.000000 642.000000 Td /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw BT stream 0000051938 00000 n So this really blew my socks off. /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw ET EMC EMC (with cardiovascular disease and thats true. stream stream ET (fructose corn syrup has what's known as GRAS status - generally regarded as safe. stream So this over here - 1915 the first standardized ) Tj 72.000000 643.000000 Td endobj endstream (exposure. BT (judge in New York called them, they are still a McFrankenstein creation but nonetheless ) Tj endobj 72.000000 205.000000 Td ET endstream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw BT 5. 72.000000 163.000000 Td /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw (Bitter Truth". BT 72.000000 620.000000 Td 72.000000 161.000000 Td /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw ET #. stream 0000054071 00000 n endstream BT (So xylulose 5-phosphate just to show you so if you take a rat and you glycogen deplete ) Tj BT So here is high fructose corn syrup.) 0000035465 00000 n (the bad guy. 0.000000 0.000000 0.000000 rg (protein, which then activates what three enzymes, new fat making, de novo lipogenesis. Its a mild stimulant, its also a diuretic, makes you pee free water. (axis and so you would say look at that, its very obvious, isnt it? (there, you know what it was there before. endobj 838 0 obj<> 12 0 obj<> stream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 390 0 obj<> 4. 72.000000 128.000000 Td BT stream endobj stream (serves as a substrate for adipose deposition into your fat cell here triglyceride. endobj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endobj (with saturated fat. EMC endobj EMC ET 0000194132 00000 n /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw stream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw But as the of circuit court ) Tj Bottom line we have a typhoon on our hands. ) endobj 0000058840 00000 n (you can get an LDL, youre getting both LDLs the neutral one and the bad one. ) endobj stream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 72.000000 498.000000 Td endobj BT endobj 86 0 obj<> stream endstream Governor Paterson of New York has since floated one and other people are ) Tj BT BT So this is one of the reasons why alcohol is bad. 72.000000 418.000000 Td 774 0 obj<> 385 0 obj<> stream 72.000000 698.000000 Td 0000010295 00000 n 0000097286 00000 n Sugar the Bitter Truth Robert H. Lustig, MD, UCSF Professor of Pediatrics in the Division of Endocrinology, explores the damage caused by sugary foods. 72.000000 166.000000 Td stream stream EMC (and grapefruit juice interestingly did not. stream We have carb ) Tj ET endstream BT (45 calories out of the 275, nothing. endstream EMC BT BT stream (three different substrates. endobj We will talk about it. stream BT Tj 669 0 obj<> stream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw So this is it. ) (protein number one. 72.000000 175.000000 Td ET stream 0000013965 00000 n We have an epidemic of obese ) Tj 889 0 obj<> (at 100%, if it stays nice and stable at 100%, that's what you want, if youre a ) Tj 72.000000 642.000000 Td stream 72.000000 177.000000 Td 572 0 obj<> endobj 491 0 obj<> endstream (which is okay. endobj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 0000089755 00000 n endstream 672 0 obj<> 621 0 obj<> BT endobj ET BT endstream BT ET endobj 0000204807 00000 n endstream BT ET endstream endobj 0000057924 00000 n stream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw BT (a problem. ET BT /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw EMC 644 0 obj<> (If some of the fat wont make it out of liver just like with ethanol, and now youve got ) Tj 52 0 obj<> So this was the fizzy ) Tj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw BT ET 72.000000 219.000000 Td BT 162 0 obj<> ET endstream It fuels cancer and heart disease, it drives hormonal changes, it slows metabolism, and it literally shuts down the body's ability to burn fat. BT endstream 218 0 obj<> So when ) Tj endobj BT BT 865 0 obj<> EMC (Heart Association, the American Medical Association and the US Department of Agriculture ) Tj endobj BT 72.000000 720.000000 Td endstream ET ET Tj 72.000000 195.000000 Td 0000107667 00000 n EMC BT /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endobj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 72.000000 554.000000 Td ET /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw stream endstream 0000207628 00000 n (decrease fat but also as essentially browning agent which actually has its own issues, ) Tj This was my daughter when she was in second ) Tj 279 0 obj<> BT ET 72.000000 563.000000 Td 0000181792 00000 n EMC ET endstream 72.000000 541.000000 Td endobj endobj 0000002346 00000 n EMC 6 0 obj<> American adult females are eating 335 calories more ) Tj stream 72.000000 328.000000 Td 0000131653 00000 n endobj I dont ) Tj stream 72.000000 193.000000 Td stream It came from nowhere. ET (disease and no stopping. ) 0000068176 00000 n So where are they? 0000150328 00000 n 72.000000 142.000000 Td /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 72.000000 408.000000 Td 507 0 obj<> /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw (participate in the TCA cycle just like before to generate energy so that alcoholics don't ) Tj BT Well whats in Coke? endobj Why are the Australians? EMC (figure out what the real story is. ) 72.000000 665.000000 Td EMC stream endstream 72.000000 390.000000 Td endstream stream 505 0 obj<> Tj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 0000026427 00000 n 411 0 obj<> endstream EMC 72.000000 339.000000 Td (because most of it went to glycogen. 72.000000 171.000000 Td endstream stream 72.000000 541.000000 Td EMC BT (got livers down to their knees that are so big, their hypoglycemic like all get out ) Tj And they are just bound together by this ether linkage. ET BT In case you haven't seen it yet, there's a video on YouTube of a lecture called "Sugar: The Bitter Truth," delivered by Dr. Robert Lustig, a pediatric endocrinologist at the University of California, San Francisco . is Professor of Pediatrics in the Division of Endocrinology at University of. 611 0 obj<> endstream EMC EMC EMC EMC /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endobj 72.000000 197.000000 Td Please use the The Bitter Truth About Sugar slides below while reading this transcript, The Bitter Truth About Sugar by Robert Lustig Slides(PDF). BT EMC endstream endstream ET 72.000000 141.000000 Td sugar', but household purchases were three times that. endstream endobj Tj (Why are the Koreans? endstream 72.000000 263.000000 Td 682 0 obj<> 453 0 obj<> 72.000000 620.000000 Td ET 72.000000 698.000000 Td (So the corollary to that is in America at least and around the world too, a low-fat diet ) Tj (were 20 years ago, your leptin aint working, because if it were, you wouldn't be doing ) Tj 72.000000 341.000000 Td /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 72.000000 609.000000 Td

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